Charles Barkley and Shaquille O'Neal have developed a nice rivalry over the years, and it came to a head once again over the weekend during CBS Sports' March Madness coverage.

During halftime of a game, Shaq tweeted an insult at Sir Charles.

Since Barkley had the platform of a nationally-televised broadcast, he fired back and had his fellow commentators cracking up.

At one point, he even said that a cream soda that Shaq endorses is "spreading diabetes all across the world".

Brilliant!